Analysis of protein interaction and function with a 3-dimensional MALDI-MS protein array

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Analysis of protein interaction and function with a 3-dimensional MALDI-MS protein array.

Protein profiling and characterization of protein interactions in biological samples ultimately require indicator-free methods of signal detection, which likewise offer an opportunity to distinguish specific interactions from nonspecific protein binding. Here we describe a new 3-dimensional protein microchip for detecting biomolecular interactions with matrix-assisted laser desorption-ionizatio...

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ژورنال

عنوان ژورنال: BioTechniques

سال: 2005

ISSN: 0736-6205,1940-9818

DOI: 10.2144/05391rr02